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Vollset SE1 et al. Abstract BACKGROUND: Some countries fortify flour with folic acid to prevent neural tube defects but others do not, partly because of concerns about possible cancer risks. We aimed […]

Scaglione F1, Panzavolta G. Author information Abstract Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism. Mammals cannot synthesize folate and depend on supplementation to maintain normal […]

Pietrzik K1, Bailey L, Shane B. Abstract There is a large body of evidence to suggest that improving periconceptional folate status reduces the risk of neonatal neural tube defects. […]

Obeid R1, Holzgreve W, Pietrzik K. Abstract Women have higher requirements for folate during pregnancy. An optimal folate status must be achieved before conception and in the first […]

Papakostas GI1, Shelton RC, Zajecka JM, Etemad B, Rickels K, Clain A, Baer L, Dalton ED, Sacco GR, Schoenfeld D, Pencina M,Meisner A, Bottiglieri T, Nelson E, Mischoulon D, Alpert JE, Barbee JG, Zisook S, Fava M. Abstract OBJECTIVE: The authors conducted two multicenter […]

Bortolus R1, Blom F, Filippini F, van Poppel MN, Leoncini E, de Smit DJ, Benetollo PP, Cornel MC, de Walle HE, Mastroiacovo P;Italian and Dutch folic acid trial study groups. BACKGROUND: In 2010 a Cochrane review confirmed […]

Roffman JL1, Lamberti JS, Achtyes E, Macklin EA, Galendez GC, Raeke LH, Silverstein NJ, Smoller JW, Hill M, Goff DC. Abstract IMPORTANCE: More effective treatments are needed for negative symptoms of schizophrenia, which are typically chronic, […]